Radiology Differential Diagnosis Tool
RadReason is a radiology differential diagnosis tool that turns dictated imaging findings into structured, ranked differentials in real time — built to support clinical reasoning during the read, not replace it.
What is differential diagnosis in radiology?
A radiology differential diagnosis is the ranked list of possible entities that could explain a given set of imaging findings. Building a strong differential is one of the central cognitive tasks of the read — it shapes the impression, the recommended follow-up, and the downstream clinical workup.
A good differential is not just a list. It is structured: the most likely entities first, the must-not-miss diagnoses surfaced even when unlikely, and the reasoning behind each entry kept tight enough to fit into a dictated impression.
Why radiology differentials are challenging
Building a high-quality differential under time pressure is hard. The constraints are familiar to anyone reading a list:
- Imaging findings are often nonspecific — the same pattern can map to a long differential.
- Anchoring on the first entity that fits is easy, especially on routine cases.
- Rare or low-prevalence entities are exactly the ones that matter when they're the answer.
- The clinical context that would change the differential isn't always available at the workstation.
How RadReason helps generate structured differentials
RadReason is built around the dictation moment. You speak the imaging findings you see, and the assistant returns a structured radiology differential diagnosis with brief, traceable reasoning for each entity. The goal is to give you a second perspective at the exact point where it would change a read, without forcing you out of your existing dictation workflow.
The differential is a starting point for your own reasoning, not a final answer. Final interpretation always remains with the radiologist.
Quick Diff vs Learn Mode
RadReason exposes two modes for working through a differential:
- Quick Diff — dictate, get a ranked differential, move on. Built for speed during routine reads.
- Learn Mode — same starting point, plus targeted follow-up questions that push you to think through what would narrow the differential. Optional board-style questions are layered on top for active learning.
Example workflow
You dictate"Lobulated mesenteric mass with internal calcifications and mild adjacent fat stranding."
RadReason returnsA ranked differential — carcinoid tumor, sclerosing mesenteritis, desmoid, lymphoma — with brief imaging-feature reasoning for each entity.
In Learn Mode"Is there a desmoplastic reaction or retractile change?" and a board-style follow-up tied to the same case.
The example is illustrative. Actual output varies by the findings you describe and the level of detail you provide.
Try the differential diagnosis tool
RadReason is private by default — dictated audio and transcripts are processed in memory and not stored, so nothing from your dictation lands in our database. Open the app to dictate a case and see the differential workflow end-to-end.